There are a handful of foundational concepts that every machine learning enthusiast learns early on, such as getting rid of non-informative and redundant features. Optimizing your model's hyperparameters is time well-spent.
Continue readingAs the COVID-19 pandemic, driven by the SARS-CoV-2 virus, continues, scientists around the globe have collectively come together to develop potential therapeutics against the virus, in addition to the currently available vaccines.
Continue readingMetabolic differences in delirium prone patients lead to a protein with computationally shown possibility for binding to Sars-CoV2 spike protein.
Continue readingSphingolipids are a very diverse class of lipids that play many important functions in the life of a cell. However, their accumulation can be detrimental and can lead to the development of neurologic and metabolic disorders.
Continue readinglucosylceramides (GlcCers) and galactosylceramides (GalCers) are structurally related lipids that are important for mammalian cells. However, their presence in the body is tissue-specific, and problems with the body’s ability to maintain the right balance of theses lipids can lead to devastating but drastically different diseases.
Continue readingParkinson's disease (PD) is projected to affect up to 9 million people worldwide by 2030, with the ultimate cause behind 90% of these cases remaining a black box. While the pathomechanisms underlying Parkinson’s disease have still not been elucidated, recent research is pointing more and more towards the involvement of lipids in the development and progression of PD, including cytotoxic interactions with the protein α-synuclein (the accumulation of which is the major pathological hallmark of PD) and dysregulation of lipid pathways.
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